Which condition is described as painful, itchy, and characterized by the appearance of lesions?

Eczema is a condition that fits the description provided in the question. It is known for causing discomfort, including pain and intense itching, which can significantly affect an individual's quality of life. The condition appears with various types of lesions, which are often red, inflamed, and may ooze or become crusty. Eczema is an inflammatory skin condition that arises from a combination of genetic and environmental factors and primarily affects the skin's ability to retain moisture, leading to dry and irritated skin.

In contrast, a pustule refers to a small, inflamed, pus-filled lesion, typically associated with acne or infections, but it does not encompass the chronic, itchy, and dry nature of eczema. A macule is a flat, discolored spot on the skin that is not raised or itchy, while the term "lesion" is a broad term that can refer to any abnormal change in the skin but lacks the specific symptoms of pain and itchiness. Thus, eczema is the most accurate choice given its defining characteristics.